Sherouk Mohamed Tawfik

Ph.D. Student (2022-2027)

Department of Pharmaceutical Sciences

Education

2011-2016
BSc. Pharmacy
Ain Shams University
2018-2021
MSc. Biochemistry
The American University in Cairo, School of Sciences and Engineering
2022-2027
Ph.D. Student in Pharmacology
University of Connecticut School of Pharmacy

 

Working Experience

2014
Quality Assurance Trainee, Pfizer, Egypt
2016-
Assistant Lecturer, Department of Pharmacology and Biochemistry, The British University in Egypt
2018-2019
Teaching Assistant, General Science Laboratory, The American University in Cairo
2022
Graduate Assistant, Department of Physiology and Neurobiology, University of Connecticut

 

Honors and Awards

2012
Best Presenter Award, Competition held at the Children’s Cancer Hospital
2016
Academic Honor Award, Ain Shams University
2018-2020
Laboratory Instruction Fellowship, The American University in Cairo
2019
Graduate Student Research Grant, The American University in Cairo
2021
Graduate Academic Honor, The American University in Cairo
2023
2nd Place of Best Presentation Award Predoctoral Research in the 25th North American ISSX Meeting in Boston, Massachusetts, September 10-13, 2023
2023
Travel Award in the 25th North American ISSX Meeting in Boston, Massachusetts, September 10-13, 2023
2024
Travel Award in the 26th North American ISSX Meeting in Honolulu, Hawaii, September 15-18, 2024

 

Poster Presentations

03/2022
Research and Creativity Convention, The American University in Cairo
Tawfik SM, Abdollah MR, Elmazar M, El-Fawal HA, & Abdelnaser A. Effects of metformin combined with antifolates on HepG2 cell metabolism and cellular proliferation
09/2022
ISSX/MDO 2022 Meeting, Seattle, WA
Tawfik SM, Migliorati JM, and Zhong XB. A mega-analysis on ADME and toxicity of inotersen, patisiran, and vutrisiran for the treatment of hereditary transthyretin-mediated amyloidosis
09/2022
ISSX/MDO 2022 Meeting, Seattle, WA
Migliorati JM, Tawfik SM, and Zhong XB. A direct systematic comparision of therapeutic efficacy of antisense oligonucleotide and small interfering RNA drugs in in vitro models
09/2023
25th North American ISSX Meeting, Boston, MA
Tawfik SM, Nguyen LTG, and Zhong XB. Unveiling the intracellular journey: GOLGA8N-mediated subcellular trafficking of siRNA drugs and its implication on silencing efficacy
09/2024
26th North American ISSX and 39th JSSX Meeting, Honolulu, Hawaii
Tawfik SM, Nguyen LTG, Jin J, Armanios B, and Zhong XB. Unraveling the impact of metabolic dysfunction-associated steatohepatitis on the therapeutic efficacy of FDA-approved siRNA drugs

 

Publications

Khattab AR, Guirguis HA, Tawfik SM, & Farag MA. Cheese ripening: a review on modern technologies towards flavor enhancement, process acceleration, and improved quality assessment. Trends in Food Science & Technology, 2019, 88:343-360.

Farag MA, Abib B, Tawfik SM, Shafik N, and Khattab AR. Caviar and fish roe substitutes: current status in exploring their bio-chemical diversity, processing and storage as contributors of product quality and future perspectives. Trends in Food Science & Technology, 2021, 110:405-417.

Tawfik SM, Abdollah MR, Elmazar M, El-Fawal HA, & Abdelnaser A. Effects of metformin combined with antifolates on HepG2 cell metabolism and cellular proliferation. Frontiers in Oncology, 2022, 12:828988. Article published in e-book, (2022) Metabolism Meets Function: The Multifaced Role of Metabolism in Cancer. Lausanne: Frontiers Media SA. DOI:10.3389/978-2-88976-243-9.

Abdelzaher HM, Tawfik SM, Nour AA, Abdelkader SI, Elbalkiny ST, Abdelkader M, Abbas WA, and Abdelnaser A. Climate change, human health, and the exposome: utilizing OMIC technologies to navigate an era of uncertainty. Frontiers in Public Health, 2022.

Liu A, Zhao J, Shah M, Migliorati JM, Tawfik SM, Bahal R, Rasmussen TP, Manautou JE, and Zhong XB. Nedosiran, a candidate siRNA drug for the treatment of primary hyperoxaluria: design, development, and clinical studies. ACS Pharmacol Transl Sci, 2022, 5(11):1007-1016. PMID:36407951. PMCID:PMC9667536. DOI:10.1021/acsptsci.2c00110.

Gogate A, Belcourt J, Shah M, Wang AZ, Frankel A, Holly K, Chalon M, Stephen P, Kolli A, Tawfik SM, Jin J, Bahal R, Rasmussen TP, Manautou JE, and Zhong XB. Targeting the liver with nucleic acid therapeutics for the treatment of systemic diseases of liver origin. Pharmacological Reviews, 2024, 76(1):49-89. PMID:37696583. PMCID: PMC10753797. DOI:10.1124/pharmrev.123.000815.

 

Contact Information
Emailsherouk.tawfik@uconn.edu
Phone860-486-6803
Mailing AddressDepartment of Pharmaceutical Sciences, School of Pharmacy, University of Connecticut, 69 North Eagleville Road, Storrs, CT 06269
Office LocationPBB-230A