Pei Wang

Visiting Ph.D. Student (2017-2019)

Current position: Faculty, School of Medicine in Zhengzhou University


Education

2009-2013
BSc. in Pharmacy
Zhengzhou University
2013-2016
MSc. in Pharmacy
Zhengzhou University
2016-2020
Ph.D. student in Pharmacology
Zhengzhou University
2017-2019
Visiting Ph.D. student in Pharmacology
University of Connecticut

 

Working Experience

2020-
Faculty
School of Medicine, Zhengzhou University, Zhengzhou, China

 

Awards and Honors

2010
Third-class Scholarship in Zhengzhou University
2011
Third-class Scholarship in Zhengzhou University
2011
Excellent Student in Zhengzhou University
2013
First-class Scholarship in Zhengzhou University
2014
First-class Scholarship in Zhengzhou University
2015
First-class Scholarship in Zhengzhou University
2016
Academic Scholarship of Henan
2017
Academic Scholarship of Henan
2017-2019
National Academic Scholarship of China
2019
A Graduate Student Travel Award ($800) from ASPET at the Experimental Biology Meeting in Orlando, FL

 

Oral Presentations

03/2019
58th Annual Meeting of SOT, Baltimore, MD
Consequences of neonatal activation of PXR on drug metabolism in adult mice

 

Poster Presentations

10/2016
21st International Symposium on Microsomes and Drug Oxidations, Davis, California
Wang P, Nei YL, Wang SJ, Zhang LR. Post-transcriptional Regulation of UGT1A1 Expression by miR-298
04/2019
Experimental Biology Meeting, Orlando, FL
Wang P, Shao X, Bao Y, Chen L, Zhang L, and Zhong XB. Impacts on hepatic ontogenic expression of drug-metabolizing enzymes by high-fat diet-induced obesity in mice

 

Publications

Wang R, Zhang PJ, Zhai XX, Xu W, Wang P, Xue BY, Zhang Y, Li XT. Comparison of daphnoretin content among different habitats of root bark medicinal material of Daphne Genkwa. China Pharmaceuticals, 2014, 23(23):50-51.

Wang P, Li XT, Zhang LR. Post-transcription regulation of drug metabolic enzymes by miRNAs, Chinese Pharmacological Bulletin, 2015, 31(8): 1037-1040.

Han SN, Wang P, Zhang W, Zhang LR. Effects of midazolam on hERG K+ channel, Chinese Journal of Applied Physiology, 2015, 31(2):143-147.

Wang P, Li JF, Zhang SJ, Wang SJ, Li XT, Zhang LR. Effect of CYP2B6*6 polymorphism on pharmacokinetics of efavirenz in Chinese, Chin J New Drugs Clin Rem, 2016, 35(2): 131-137.

Wang SJ, Wang P, Li XT, Zhang LR. Drug-induced liver injury: metabolic and genetic basis, Chinese Pharmacological Bulletin. 2016, 32(7):902-905.

Zhao YL, Yang WH, Yan L, Wei LM, Wang P, Zhang W, Zeng ZS, Zhang LR. Construction of eukaryotic expression vector of CYP3A4 intron 10 promoter regulated by CYP3A4* 1G. Journal of Zhengzhou University (Medical Sciences), 2016, 51(2):153-157.

He H, Wang P, Li SG, Cheng YL, Kan QC, Zhang LR. Effects of pargyline on histone methylation in promoter and enhancer regions and transcription of CYP3A4/3A7. Acta Pharmaceutica Sinica, 2017, 52(1):91−98. PMID:29911787.

Nei YL, He H, Li JF, Meng XG, Yan L, Wang P, Wang SJ, Bi HZ, Zhang LR, Kan QC.Hepatic expression of transcription factors affecting developmental regulation of UGT1A1 in the Han Chinese population. Eur J Clin Pharmacol, 2017, 73:29–37. PMID:27704169. DOI:10.1007/s00228-016-2137-7.

Wang P, Nie YL, Wang SJ, Yang LL, Yang WH, Li JF, Li XT, Zhang LR. Regulation of UGT1A expression by miR-298 in human livers from the Han Chinese population and in human cell lines. Epigenomics, 2018, 10(1):43-57. PMID:29172698. DOI:10.2217/epi-2017-0068.

Wang Y, Yan L, Liu J, Chen S, Liu G, Nie Y, Wang P, Yang W, Chen L, Zhong XB, Han S, and Zhang L. The HNF1α-regulated lncRNA HNF1α-AS1 is involved in the regulation of cytochrome P450 expression in human liver tissues and Huh7 cells. The Journal of Pharmacology and Experimental Therapeutics, 2019, 368(3):353-362. PMID:30602592. PMCID:PMC6367688. DOI:10.1124/jpet.118.252940.

Wang P, Liu G, Nie Y, Han S, Li J, Zhong XB, and Zhang L. Epigenetic memory is involved in the persistent alterations of drug-processing genes in adult mice due to PCN-activated PXR during early life. Toxicological Sciences, 2019, published on line in August 6. PMID:31388680. DOI:10.1093/toxsci/kfz177.

Chen L, Wang P, Bahal R, Manautou JE, and Zhong XB. Ontogenic mRNA expression of RNA modification writers, erasers, and readers in mouse liver. PLoS One, 2019, 14(12):e0227102. PMID:31891622. DOI:10.1371/journal.pone.0227102.

Wang P, Shao X, Bao Y, Zhu J, Chen L, Zhang L, Ma X, and Zhong XB. Impact of obese levels on the hepatic expression of drug-processing genes in adult and offspring mice. Acta Pharmaceutica Sinica B, 2020, in press, DOI:10.1016/j.apsb.2019.10.009.

Chen L, Wang P, Manautou JE, and Zhong XB. Knockdown of lncRNAs HNF1α-AS1 and HNF4α-AS1 alters susceptibility of acetaminophen-induced cytotoxicity in HepaRG cells. Molecular Pharmacology, 2020, publish on line. DOI:10.1124/mol.119.118778.

Contact Information
Emailpei.2.wang@uconn.edu
Phone860-486-6803
Mailing AddressDepartment of Pharmaceutical Sciences, School of Pharmacy, University of Connecticut, 69 North Eagleville Road, Storrs, CT 06269
Office LocationPBB-230A