Jing Jin

Ph.D. Candidate (2021-2026)

Department of Pharmaceutical Sciences


Education

2013-2017
BSc. in Animal Sciences
Yangzhou University
2017-2020
MSc of Animal Genetics and Breeding
Yangzhou University
2021-2024
Ph.D. Student in Pharmacology
University of Connecticut
2024-2026
Ph.D. Candidate in Pharmacology
University of Connecticut

 

Working Experience

2016
Visiting Scholar, University of Western Australia, Perth, Australia

 

Professional Societies

2021-
Student Member, American Society of Pharmacology and Experimental Therapeutics (ASPET)
2022-
Student Member, International Society for the Study of Xenobiotics (ISSX)

 

Honors and Awards

2016
First Prize of National Animal Science Professional Skills Competition
2017
Outstanding Undergraduate in Yangzhou University
2017
Freshman Scholarship for Postgraduate Study
2018
Second-Class Scholarship for Postgraduate Study
2019
Merit Student in Yangzhou University
2019
First-Class Scholarship for Postgraduate Study
2020
Outstanding Graduate in Yangzhou University
2022
John Morris Graduate Student Travel Award to attend the 24th International Symposium on Microsomes and Drug Oxidations (MDO) and 13th International Meeting of the International Society for the Study of Xenobiotics (ISSX) in Seattle, September 11-14, 2022.
2023
John Morris Graduate Student Travel Award to attend the 2023 ASPET Annual Meeting in St. Louis, May 18-21, 2023.
2023
Drug Metabolism and Disposition Highlighted Trainee Author in June 2023.
2024
Philip Rosenberg and Steven D. Cohen Fellowship Award

 

Poster Presentations

09/2022
ISSX/MDO 2022 Meeting, Seattle, WA
Jin J and Zhong XB. Determination of the roles of long non-coding RNAs HNF1A-AS1 and HNF4A-AS1 in response to drug induction of cytochrome P450 expression
05/2023
ASPET Annual Meeting, St. Louis, MO
Jin J and Zhong XB. Identification and functional characterization of alternative transcripts of lncRNA HNF1A-AS1 and their impacts on drug metabolism
05/2023
ASPET Annual Meeting, St. Louis, MO
Nuyen LT, Jin J, and Zhong XB. Identification and functional characterization of alternative transcripts of lncRNA HNF4A-AS1 and their impacts on drug metabolism
05/2023
New England Drug Metabolism Discussion Group Annual Meeting, Boston, MA
Jin J and Zhong XB. Identification and functional characterization of alternative transcripts of lncRNA HNF1A-AS1 and their impacts on drug metabolism
09/2024
26th North American ISSX and 39th JSSX Meeting, Honolulu, Hawaii
Jin J, Armanios B, Nguyen LTG, Tawfik SM, Kolli A, and Zhong XB. Unraveling the role of HNF1A-AS1 in hepatocyte maturation and subnuclear space organization

 

Oral Presentations

12/2017
Jiangsu Association of Animal Science and Veterinary Medicine Annual Scholar Conference, Jiangsu, China
The Lbc gene promotes differentiation of chicken embryo stem cell into spermatogonial stem cells via Hoxa5.

 

Publications

Zhao R, Jin J, Sun X, Jin K, Wang M, Ahmed MF, & Li B. The establishment of clonally derived chicken embryonic fibroblast cell line (CSC) with high transfection efficiency and ability as a feeder cell. Journal of cellular biochemistry, 2018, 119(11):8841-8850. PMID:30076744. DOI:10.1002/jcb.27137.

Jin J, Zhao R, Chen C, Zhou J, Lu Z, Jin K, & Li B. The Lbc gene promotes differentiation of chicken embryo stem cell into spermatogonial stem cells via the regulation of transcriptional factor Hoxa5. Journal of Cellular Biochemistry, 2019, 120(5):6952-6961. PMID:30656739. DOI:10.1002/jcb.27760.

Zuo Q, Jin J, Jin K, Sun C, Song J, Zhang Y, & Li B. Distinct roles of retinoic acid and BMP4 pathways in the formation of chicken primordial germ cells and spermatogonial stem cells. Food & function, 2019, 10(11):7152-7163. PMID:31596288. DOI:10.1039/c9fo01485c.

Zuo Q, Jin J, Jin K, Zhou J, Sun C, Song J, & Li B. P53 and H3K4me2 activate N6‐methylated LncPGCAT‐1 to regulate primordial germ cell formation via MAPK signaling. Journal of Cellular Physiology, 2020, 235(12):9895-9909. PMID:32458486. DOI:10.1002/jcp.29805.

Jin K, Li D, Jin J, Song J, Zhang Y, Chang G, & Li B. C1EIP functions as an activator of ENO1 to promote chicken PGC formation via the inhibition of Notch signaling pathway. Front Genet. 2020, 11:751. PMID:32849782. PMCID:PMC7396672. DOI:10.3389/fgene.2020.00751.

Wang S, Yuan X, Zhou J, Jin J, Zuo Q, and Li B. Comparison of the effects of three cryoprotectants on the cryopreservation of mouse subcutaneous tissue under different conditions. Exp Ther Med, 2020, 20(4):3285-3289. PMID:32855699. DOI:10.3892/etm.2020.9076. Epub 2020 Jul 29.

Jiang J, Chen C, Cheng S, Yuan X, Jin J, Zhang C, Sun X, Song J, Zuo Q, Zhang Y, Chen G, and Li B. Long noncoding RNA lncPGCR mediated by TCF7L2 regulates primordial germ cell formation in chickens. Animals (Basel), 2021, 11(2):292. PMID:33498947. DOI:10.3390/ani11020292.

Zuo Q, Jin J, Zhou J, Zhang Y, Wei W, Chen G, and Li B. Dual regulatory actions of LncBMP4 on BMP4 promote chicken primordial germ cell formation. EMBO Rep, 2022, 23(1):e52491. PMID:34747116. DOI:10.15252/embr.202152491

Migliorati JM, Jin J, and Zhong XB. Drug of the Month: siRNA drug Leqvio (inclisiran) to lower cholesterol. Trends in Pharmacological Sciences, 2022, 43(5):455-456. PMID:35307191. DOI:10.1016/j.tips.2022.02.003.

Jin J and Zhong XB. 50th anniversary celebration collection: Epigenetic mechanisms contribute to intraindividual variations of drug metabolism mediated by cytochrome P450 enzymes. Drug Metabolism and Disposition. 2023, 51(6):672-684. PMID:36973001. DOI:10.1124/dmd.122.001007.

Jin J, Armanios B, and Zhong XB. LncRNA MALR drives liquid–liquid phase separation to promote esophageal cancer process. The Non-Coding RNA Journal Club: Highlights on Recent Papers—12. Noncoding RNA, 2023, 9(2):28. PMID:37104010. PMCID:PMC10144170. DOI:10.3390/ncrna9020028.

Jin J and Zhong XB. ASO drug Qalsody (tofersen) targets amyotrophic lateral sclerosis. Trends in Pharmacological Sciences. 2023, 12:S0165-6147(23)00178-5. PMID:37709589. DOI:10.1016/j.tips.2023.08.008.

Gogate A, Belcourt J, Shah M, Wang AZ, Frankel A, Holly K, Chalon M, Stephen P, Kolli A, Tawfik SM, Jin J, Bahal R, Rasmussen TP, Manautou JE, and Zhong XB. Targeting the liver with nucleic acid therapeutics for the treatment of systemic diseases of liver origin. Pharmacological Reviews, 2024, 76(1):49-89. PMID:37696583. PMCID:PMC10753797. DOI:10.1124/pharmrev.123.000815.

Jin J, Nguyen LTG, Wassef A, Sadek R, Schmitt TM, Guo GL, Rasmussen TP, and Zhong XB. Identification and functional characterization of alternative transcripts of lncRNA HNF1A-AS1 and their impacts on cell growth, differentiation, liver diseases, and in response to drug induction. Noncoding RNA, 2024, 10,28. PMID:38668386. PMCID:PMC11053763. DOI:10.3390/ncrna10020028.

Jin J, Nguyen LTG, Wassef A, Sadek R, Schmitt TM, Guo GL, Rasmussen TP, and Zhong XB. Correlations of lncRNA HNF4A-AS1 alternative transcripts with liver diseases and drug metabolism. Drug Metabolism and Disposition, 2024, DMD-AR-2024-001873. PMID:39168525. DOI:10.1124/dmd.124.001873.

Jin J, Armanios B, Nguyen LTG, and Zhong XB. Epigenetic regulation of drug metabolism and transport by long noncoding RNAs. Pharmacoepigenetics, 2nd Edition. Elsevier, Hardback ISBN: 9780443187223. eBook ISBN: 9780443187230.

 

Contact Information
Emailjingjin.w@uconn.edu
Phone860-486-6803
Mailing AddressDepartment of Pharmaceutical Sciences, School of Pharmacy, University of Connecticut, 69 North Eagleville Road, Storrs, CT 06269
Office LocationPBB-230A